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9 July 2026 | Issue 3.20 

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Welcome

 

Breaking Through the Bitterness Bottleneck

 

Oral drug products have helped improve the lives of many patients, offering treatment in a convenient and easy to manage way; however, if the finished drug is unpalatable, patients can be reluctant to adhere to treatment and their symptoms or condition can worsen. Given the fact that most active ingredients have an unpleasant or bitter taste, the pharmaceutical industry has been required to adopt approaches that can mask the flavor and improve the overall experience for the patient without negatively impacting the therapeutic effect of the drug. 

 

There is a direct and strong link between palatability of a drug and the tolerability of whether or not a patient can take the drug, particularly in certain patient populations, emphasizes Nathan H. Dormer, Ph.D., Senior Director, Drug Product Development at Adare Pharma Solutions. “Patient-centric formulations have been associated with dramatic adherence improvements among children and older adults. Older patients often report skipping or delaying doses because of difficulty swallowing, of which taste can be a factor,” he says.

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Featured Stories

From-the-editor

The Pragmatic AI Pivot

Recent AI-related news is signaling a shift in the bio/pharma industry’s digital transformation from speculative molecule generation toward grounded biological context and downstream manufacturing execution.

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Expansion 4

Cyllene Therapeutics Successfully Raises Millions to Advance Genetic Medicine Candidate

The biotech, which was formerly known as EG 427, will use the funds raised in its Series C financing round to advance its lead precision genetic medicine candidate, EG110A. 

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Dealmaking 4

Adragos Pharma and Towa Partner Up to Boost Supply of Off-Patent Drugs

Under the terms of the deal, Adragos Pharma will increase manufacturing capacity to supply Towa with up to 1.5 billion tablets annually to support reliable access to essential off patent drugs in Japan.

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Upcoming Events

AAPS Scientific Forum 2026 

Date: July 13-16, 2026

Location: Columbus, USA

Process Development & Automation for CTx Summit 2026

Date: July 14-16, 2026

Location: San Diego, USA

CRYO2026

Date: July 15-17, 2026

Location: Seattle, USA 

International Conference on Lymphocyte Engineering 2026 

Date: July 15-17, 2026

Location: Milan, Italy

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 If your company has news, insights, or a press release that deserves a wider audience, we'd love to feature it in an upcoming edition of The Pharma Navigator. 

 Get in touch to be considered for a future feature. 

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